I pack them year after year as well...just in case. I just looked at the Immodium tablets I have and they expired a couple years ago. Such a waste of money to buy new ones again only to throw them out later. I do have some Pepto tablets packed and hopefully that will tide me over if need be. Friends of ours are there right now and her husband has been staying close to the room as he is not feeling well. That's what got me thinking about this. Never been sick in the 15 trips we've been....hopefully we can continue our record.