utenlov - Welcome to the board. You will definitely get better advice if you give us an idea of your budget. There are tons of good, clean, safe hotels from about $50 all the way up to several $100's/night - and any would meet the requirement of on the beach walking distance to good restaurants, bars, and nightlife. The same with food - do you tend toward local food where the locals, and us budget tourists, eat - or do you like high-end dining? You can eat well at places where $30 is enough for all 3 meals, all the way up to places where that will barely even cover just dinner.
Don't worry about getting around - there are route taxis all over during the day and early evening, and regular taxis at closing times.
To acquaint yourself with the area, and see where hotels/bars/restaurants are that get recommended, this map is one many of us use: http://www.maherconsulting.com/negri...p2011final.pdf
For nightlife, there are way more than a couple of spots. There are live and DJ beach parties every night of the week, usually a couple parties each night - most regularly scheduled depending on the night. Here is a good listing of that to print out and take with you - http://www.negrilonestop.com/negril_nightlife.shtml
A couple parties that are not mentioned there, but many locals attend:
Sunday night beach party at the park near the craft market - dancehall
Rocky Wednesday Party at On the Rocks on the cliffs - DJ
But there are also random parties and sometimes big acts that come thru - notices for thost get posted on billboards at the round-a-bout.
A good way to meet fellow Negrilaholics, who can give you advice and fill you in on the latest goings on, is to attend Rob's live webcasts.
Here is website with his schedule - http://realnegril.com/
Enjoy your trip to Negril!