I would be comfortable walking anywhere within 5 minutes of Villa Sur Mer at night. The immediate area is well populated with businesses and relatively well lit. There is also less traffic on that end of town so cars are less of an issue. Places I would consider walk-able are: Mango Tree, LTU, Catcha, Kool Vybes, and Shark's. Walking any further north might be a stretch and I would take a taxi. Going south of VSM (i.e. toward Murphy's and Just Natural) gets dark and desolate and I would take a taxi in that direction, as well.
Of course, I would also bring a flashlight on any nighttime walk.