We went a few years ago and combined Appleton, YS Falls and the Black River in the same day. We stopped somewhere for lunch and toured Sandals @ Whitehall and made it back to Negril probably about 7pm.

The Appleton tour starts with 1 (strong) rum punch and ends with an all-you-care-to-drink tasting of almost any of their products (the 21YO was not included).