I could never pack for 12 days in two carry ons. Are you planning on buying souvenirs? When I pack I always keep in mind I need to leave room because I always come back with more than when I left. Last trip we left all of our toiletries behind to free up room. Im sure plenty of folks could make it work with two carry ons but I also keep in mind that overhead bins are not meant for over stuffed bags,and it would suck to get to the airport, find out its to big and you have to check it anyway. Because than you could have brought yourself a real suitcase.
NPR has done a couple of stories on checking bags and overhead bins I found interesting, food for thought. Here's the links if anyone is interested http://www.npr.org/templates/story/s...ryId=147992704 and http://www.npr.org/2012/03/22/149011...re-in-overhead.