Dramamine and Bonine are decent otc motion sickness meds but they tend to make you drowsy. I get VERY motion sick when I fly even when using them. For the last 6 or 7 years I have been using the scopolamine patch. You have to see your doctor for a prescription but they are awesome. No drowsiness and no discomfort. Put one behind your ear 4-6 hours before travel and you're good to go.